Puneet Gaitonde, Ph.D.

UF Postdoctoral Associate (March 2013 to October 2014)

Currently working as a Clinical Pharmacology Lead at Pfizer Inc.


  • Ph.D. in Pharmaceutical Science, 2012; University at Buffalo, The State University of New York, USA

  • B.S. Pharmaceutical Science, 2005; University of Mumbai (Bombay College of Pharmacy)

Biographical Sketch:

Dr. Puneet Gaitonde joined the Center for Pharmacometrics and Systems Pharmacology in the Department of Pharmaceutics, University of Florida at Lake Nona (Orlando) in March 2013 as a Postdoctoral Research Associate. He worked under the mentorship of Dr. Lawrence Lesko and Dr. Stephan Schmidt on clinical and preclinical PK/PD projects involving small and large therapeutic compounds. Additionally, he assisted with the review of six book chapters and several scientific manuscripts. He is currently serving as a peer reviewer for internationally-recognized scientific journals. As a research-mentor, he is helping UF Pharm.D. students in achieving their research goals. As part of a select team of UF professionals, Dr. Gaitonde contributed towards the development of a research survey on ‘Evaluating the prevalence of pharmacogenomics in clinical practice’ that was distributed to Florida-based clinicians and pharmacists. He also contributed towards the Personalized Medicine Coalition’s ‘The Case for Personalized Medicine’ report in 2013. Dr. Gaitonde is a member of ACCP, ASCPT and ISoP professional organizations.

Dr. Gaitonde received his Ph.D. in Pharmaceutical Sciences from the University at Buffalo (SUNY-Buffalo) in 2012 under the guidance of Prof. Sathy V. Balu-Iyer. His doctoral thesis was titled ‘Mechanism of Anionic Phospholipids mediated mitigation of Immunogenicity of Recombinant Human Factor VIII’. During his doctoral research work, he has authored 6 scientific publications. One of his first-author publication was chosen as the ‘Editors’ Pick’ by the Journal of Pharmaceutical Science for contributing particularly original and significant scientific findings. He has presented his research work at several National and International scientific conferences. His research work was bestowed with the prestigious ‘Innovation in Biotechnology’ award presented by the American Association of Pharmaceutical Scientists (AAPS) at their National Biotech Conference in 2012. In addition, his doctoral work also has led to a US and European Patent filing. For his academic achievement, he was awarded with the Dr. John Kapoor Graduate Fellowship in Pharmaceutical Sciences at UB. Outside of research, he has served as the President of the Pharmaceutical Sciences-Graduate Student Association at SUNY-Buffalo, and as an abstract reviewer for several AAPS conferences.

Before joining SUNY Buffalo, he obtained his undergraduate degree in Pharmaceutical Science from the University of Mumbai (Bombay College of Pharmacy) in India. For his academic excellence, he was awarded the Sir Ratan Tata, J.R.D Tata and Unichem Inc. scholarships.


“Following my graduate studies, I was looking to gain experience in Clinical Pharmacology and Pharmacometrics. The Center for Pharmacometrics and Systems Pharmacology (CPSP) at the University of Florida provided me a unique and enriching learning platform made possible by the excellent guidance and mentorship of its esteemed faculty and staff. Furthermore, the program provided an opportunity to bridge the gap between academia and the real world setting through extensive collaborations with the pharmaceutical industry and other academic research institutes. These collaborations allowed me to acquire and hone a unique and transferrable skill set, as well as, to better understand the practical applications and implications of my knowledge. A strong emphasis on open communication and good scientific discussion also served to fortify my critical thinking and interpersonal skills.

The CPSP strongly encourages its students to pursue their interests by attending several national and international scientific conferences such as ASCPT, ACCP, ACoP and PAGE in an effort to stay current and network with people in various capacities. I have benefitted tremendously from attending a multitude of such conferences in the fields of clinical pharmacology and pharmacometrics.

I would especially like to thank Dr. Lesko, Dr. Schmidt and Dr. Trame, who through their unwavering support of my intellectual pursuits, helped to ensure that the program met my career and personal goals.”

Selected Publications/Presentations


Gaitonde P, Purohit VS, and Balu-Iyer SV. Intravenous administration of Factor VIII-O-Phospho-L-Serine (OPLS) complex reduces immunogenicity and preserves pharmacokinetics of the therapeutic protein; Eur. J. Pharm. Sci.,2014.


Zheng S, Gaitonde P, Andrew MA, Gibbs MA, Lesko LJ, Schmidt S. Model-based assessment of dosing strategies in children for monoclonal antibodies exhibiting target-mediated drug disposition. CPT Pharmacometrics Syst Pharmacol. 2014 Oct 1;3:e138. doi: 10.1038/psp.2014.38.


Gaitonde P, Miller S, Trame MN, Schmidt S. Quantitative Approaches in Translational Research: An Overview. In: Translational research methods for diabetes, obesity, and cardiometabolic drug development, Springer, New York, NY, 2014 in press.


Gaitonde P, Chin J, Ramakrishnan R, Bankert RB, and Balu-Iyer SV. Exposure to Factor VIII in the presence of Phosphatidylserine induces hypo-responsiveness towards Factor VIII challenge in Hemophilia A mice; J. Biol. Chem, 2013


2015 Scheduled – Gaitonde P, Garhyan P, Chien JY, and Schmidt S. ‘Drug-Systems-Disease model to predict treatment-outcome in Type 2 Diabetes Mellitus’; ASCPT, New Orleans, LA

2014 Presented – Gaitonde P, Biliouris K, Norris D, Schmidt S, Nestorov I, Rogge M, Lesko LJ, and Trame MN. ‘Development of a Non-Human Primate, semi-mechanistic pharmacokinetic model for pediatric dose prediction for the treatment of Spinal Muscular Atrophy’; ACoP, Las Vegas, NV

2014 Presented – Zheng S, Gaitonde P, Andrew MA, Gibbs MA, Lesko LJ, and Schmidt S. ‘Model-based comparison of monoclonal antibody dosing strategies for application in children’; ACoP, Las Vegas, NV

2014 Presented – Gaitonde P, Trame MN, Chien JY, Garhyan P, and Schmidt S. ‘Development of drug-disease model for Type 2 Diabetes Mellitus’; ACCP, Atlanta, GA

2014 Presented – Gaitonde P, Trame MN, Syvanen S, Lesko LJ, and Schmidt S. ‘Mechanism-based Evaluation of Codeine toxicity in Pediatrics’; ASCPT, Atlanta, GA